The sternal marrow aspiration of amyloid in multiple myeloma.

The bone marrow on sternal aspiration in multiple myeloma.

Atypical amyloidosis associated with nonthrombocytopenic purpura and plasmocytic hyperplasia of the bone marrow.

If!] SI 1oN PROPP, M.D., \VILLIA 1 B. SCHARFMAN, M.D., BIOHARD T. BEEBE, M.D., AND ARTHUR W. WRIGHT, M.D. T HIS REPORT is (‘oncerned with two patients whose clinical and laboratory findings were strikingly similar and unusual. Both wei’e admitted to tile hospital because of unexplained skin purpura of peculiar localization about the eyes, breasts, and thighs, which had been present for two to t...

An Unusual Presentation of Plasma Cell Leukemia with Undiagnosed Multiple Myeloma

A 54 year old man with history of cardiomyopathy and chronic fibrillation first presented with bloody diarrhea. Then during the assessment of his abnormal lab. data revealed cast nephropathy in renal biopsy, gamma peak in protein electrophoresis and fine lytic lesions in skull graphy. His bone marrow asp...

In vitro Effect of Pomalidomide on Bone Marrow Mononuclear Cells from Multiple Myeloma Patients

Background: Many features of anticancer drugs, including cytotoxicity and/or cytokine induction, are studied using cell lines orhuman blood leukocytes. However, in a disease such as multiple myeloma, most cancerous cells are resided within bone marrowmononuclear cells. In the present study, we investigated the effect of pomalidomide on apoptosis and IL-2 production of bonemarrow mononuclear cel...

Multiple myeloma in a patient with suspected hyperparathyroidism

Multiple myeloma (MM) is a clonal B-lymphocyte neoplasm of terminally differentiated plasma cells. Imaging modalities which allow the recognition of the effects of myeloma cells on the skeletal system have been utilized for a long time. Herein, we represent a patient with generalized osteoporosis and hypercalcemia, who was referred for parathyroid scan, in whom the widespread bone marrow techne...